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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Article
LachesisMutaMuta:State oftheArt
Author(s)
GrazielleDelaroliPilon1, and YokoOshima-Franco2
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DOI:10.17265/1934-7391/2021.01.001
Affiliation(s)
1. BiomedicineCourse, University of Sorocaba (UNISO), RodoviaRaposo Tavares km 92.5, Sorocaba, SP18023-000, Brazil
2.Post-GraduatePrograminPharmaceuticalSciences,UniversityofSorocaba(UNISO),RodoviaRaposoTavareskm92.5,Sorocaba,SP18023-000,Brazil
ABSTRACT
ThisarticlewascarriedouttogatheracollectionofdataextractedfromseveralstudiesaboutthesnakeLachesismutamuta(surucucu),encompassinginthisinformationfromtheeffectsandpropertiesofitsvenom,casereport,treatmentandevendiagnosis.L.m.mutawasaddressedthroughoutthestudybyreferringmainlytotheirvenom,whichinisolatedfractions,asLHFI,LHFII,LmTX-I,amongothers,presentseveralactivities,amongwhichstandoutare:coagulant,hemorrhagic,proteolyticandneurotoxic.Besides,otherstudiesinvolvingitsdiagnosis,treatment,cytotoxicity,edema,inflammation,genotoxicityandmutagenicityhavealsobeencarriedout.Thebibliographicsurveyinitiallymade,followedbytheselectionofcollecteddata,wasproperlyorganizedinthetextusingthenarrativemethod,sothatthefindingscouldbechronologicallydistributedinatimeline.Therefore,itwaspossibletoconcludethatallthesestudieswereandareofparamountimportancetohelpunderstandthepathophysiologyofenvenomingbythissnake,inadditiontopointingouttheBothrops-Lachesisantivenom,openingawidetherapeuticwindowfornumerousapplications.
KEYWORDS
Lachesismutamuta,snake venom,state oftheart.
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